Pittsburg State faculty and students are involved in a federally-funded effort to enhance biomedical research and training. This website describes the activities of the program on this campus.
The National Center for Research Resources (NCRR) in the National Institutes of Health (NIH) provides Institutional Development Awards (IDeA) to foster research within states that traditionally have not received significant levels of competitive funding from NIH. One of the approaches of the IDeA Program, and the source of support on this campus, was the Biomedical Research Infrastructure Networks (BRIN) now referred to as the Kansas IDeA Network of Biomedical Research Excellence (K-INBRE).
Pitt State K-INBRE 2024 conference attendees
The objectives of K-INBRE are to:
K-INBRE funding is also intended to strengthen the basic science departments of the undergraduate institutions in the network by involving students in research. The undergraduate institutions also serve an important "feeder" role to the science departments of graduate schools within the IDeA-eligible areas.
The lead campus for K-INBRE is the University of Kansas Medical Center. Participants in Kansas K-INBRE in addition to Pittsburg State University are Emporia State University, Fort Hays State University, Haskell Indian Nation University, Kansas State University, University of Kansas - Lawrence, Washburn University, and Wichita State University.
Campus Representative (and Faculty Mentor)
Mailing Address:
Department of Biology [or Department of Chemistry]
Pittsburg State University
1701 S. Broadway
Pittsburg, KS 66762
Each of these faculty guide undergraduate research with support from K-INBRE. But, more than just guiding research, these faculty are active mentors with each student.
My research is focused in two broad areas. First, the ways in which behavioral practitioners are educated and trained in hands-on settings, and how changes to educational or training processes can facilitate stronger applied skill sets. Second, on alterations to discrete portions of therapeutic strategies and techniques in behavioral services, specific to autism spectrum disorder. Current research activities relate to training on diagnostic evaluations and interdisciplinary collaboration, understanding factors impacting the visual analysis of data, increasing intervention service rigor, and evaluating the components of supervision and internship experiences. Interdisciplinary collaboration is welcome, as are undergraduate/graduate students who are interested in autism spectrum disorders or behavior analysis.
Contact Information: phone 620.235.4279 | Contact
My research focuses on how greenspace features in cities impact global biodiversity and human well-being. Many research findings focus on the positive impacts of the proximity, density, and use of green spaces within a resident’s living environment, many of which are associated with health and psychological indicators. However, few studies have assessed the properties of the greenspace that correlate to their benefits. My research also studies how residents perceive greenspaces, the features residents would prefer to have in their neighborhood, and how wildlife diversity responds to these features.
Contact Information: phone 620.235.4947 | Contact
Understanding the mechanisms by which tumor cells are resistant to macrophages may lead to the development of therapies which can overcome this resistance. Such a therapy could enhance the effectiveness of macrophages to reduce the occurrences of metastasis and to reject tumors. Our laboratory is currently working with various tumorigenic cell lines to identify the putative gene(s) believed to be responsible for susceptibility to macrophage-mediated cytotoxicity and chemotherapeutic agents.
Contact Information: phone 620.235.4736 | Contact
The overall goal of my research is to improve the health and quality of life for individuals with disabilities and older adults through physical activity. Investigating accurate measures of fitness and health is an additional research area to help improve the reliability and validity of fitness assessments that can be used with such a diverse population. Student research assistants are provided with opportunities to work in the Ability Lab gaining valuable experience with children and adults with disabilities and older adults, specifically individuals with intellectual and developmental disabilities. Research assistants have opportunities to conduct assessments, plan and implement interventions, and evaluate outcomes. Any students who have an interest in this research and the opportunities it can provide are welcome to reach out any time.
Contact Information: phone 620.235.4670 | Contact
Dr. Mazeyar Parvinzadeh Gashti
My lab focuses on the biomedical research interest on synthesis and functionalization of biocomposite particles by biomimetic methods for drug delivery, anticancer, antimicrobial and antifungal applications. Today, we know that biopolymer gels have been extensively used in various areas of biomedicine and pharmacotherapy. Also these gels, as model systems, are also able to change the shape and morphology of particles and tailor their biofunctionality. In biomedical research, functional hybrid particles have been considered in different areas including bone and tissue engineering, surgical instruments and medical devices, neural engineering, cancer therapy, biomechanics, and medical imaging. The investigation of the role of biopolymer-based gels in the synthesis of inorganic particles and crystals is thus important for introducing cost-effective, simple, and convenient strategies in biomedical products.
Contact Information: phone 620.235.4453 | Contact
I am an associate professor in the Department of Biology at Pittsburg state University. I am a microbiologist, and my research is based on the One Health perspective. My projects focus on various aspects of food safety, antibiotic resistance and virulence of food borne pathogens, and molecular diagnostics. A few projects deal with host-pathogen interaction in vectors such as ticks and mosquitoes. I also have projects related to restoration of environmental health. I have introduced whole genome sequence analysis and bioinformatics in the undergraduate curriculum and teaching.
Contact Information: phone 620.235.4532 | Contact
Contact Information: phone 620.235.4763 | Contact
My research background is in Cellular and Molecular Biology as well as Molecular Virology. In recent years I have mentored students who have worked on several diverse projects. These have included examining the effects of polyphenols on cancer cells survival and migration, two bioinformatic-based studies of the relationship between viruses and specific cancers as well as a preliminary studies in synthetic biology aimed at designing a lead biosensor utilizing bacteria.
Contact Information: phone 620.235.4864 | Contact
I am interested in developing biomaterials based on polysaccharides, proteins, and composites, applied as anti-adhesive and antimicrobial agents for bone and cardiovascular implants with hemocompatible activity. I work with surface modification of biomaterials, synthesis of new polymeric materials, and development of biodegradable wound dressings. I study the structure-property relationship of biomaterials and their interactions with bacteria, blood components, and cellular tissues. I focus on scaffolds (hydrogels, fibers, and films) and biomaterial surfaces for regenerative medicine, such as cardiac patches, injectable scaffolds, vascular grafts, and stent coatings.
Contact Information: phone 620.235.4424 | Contact
I am an organic polymer chemist with an extensive knowledge in polymer synthesis and testing. Currently my research is focusing on two areas. The first area is the synthesis of novel aliphatic polyesters containing biologically active molecules. These materials will be tested for antibacterial and antimicrobial properties for potential use in wound dressings or food packaging. The second area is biodegradable polymers. Microplastics are a significant problem in the environment and novel degradable materials are needed to remediate this problem.
Contact Information: phone 620.235.4494 |Contact
Recognition of foreign antigens in the human immune system is primarily performed by the B and T cell receptors. The genes encoding the antigen-binding receptors are produced in a functional form during specific stages of lymphocyte development through a specific DNA rearrangement process referred to as V(D)J recombination. This results in somatic rearrangement of the gene segments that encode the variable regions of B-cell and T-cell receptors. Two lymphoid specific proteins, RAG1 and RAG2, initiate V(D)J recombination by introducing DNA double-strand breaks between each selected gene segment and their bordering recombination signal sequence (RSS) in a two step mechanism, in which the DNA is first nicked followed by hairpin formation. Mutations in either RAG protein that disrupt catalytic activity result in fatal immunodeficiency diseases, including SCID.
Our interests continue at the molecular level and we utilize biochemical methods to further interpret the protein-DNA interactions of RAG1 with the RSS. We will employ photo-crosslinking assays to determine the DNA nucleotides in the RSS heptamer that interact with RAG1 in the presence and absence of RAG2. Overall, these studies will provide important insight into the V(D)J recombination reaction, specifically that significant interaction of the RSS heptamer with RAG1 and to further elucidate the function of RAG1 and RAG2.
Contact Information: phone 620.235.6541 | Contact
My research examines the psychological mechanisms underlying decision-making behavior from both comparative and developmental perspectives. My comparative work explores the influence of species’ ecology on their ability to solve cognitive problems and takes place at Sea Life Kansas City (fishes) and PSU’s Nature Reach (birds). My developmental work uses a game theory approach to investigate the factors influencing children’s cooperative behavior in social dilemmas. More recently, I have taken a leadership position in two newly established Big Team Science networks: ManyFishes, a multi-site collaborative research project dedicated to comparing cognitive and behavioral abilities in fishes, and ManyManys, a large-scale collaboration on comparative cognition and behavior across animal taxa.
Contact Information: phone 620.235.6152 | Contact
Human health is affected significantly by local environmental conditions. Local terrestrial ecosystems and the native fauna they support only function normally in the presence of native species of plants. Surprisingly, many areas have not been adequately surveyed for their native plant diversity, or if so, have not been re-surveyed for many decades. One aspect of my research studies the distribution of native and non-native plants across local landscapes. The data from such studies are needed by state and federal land management agencies, municipal planners, educators, ecologists and other scientists. Environmental consulting, NGOs and with state and federal land-management agencies are good career options.
Contact Information: Phone 620.235.4424 | Contact
Dr. Christopher Ward
Our lab focuses on understanding the complexities of EGFR isoforms in solid tumors, particularly their roles in cancer progression and potential as diagnostic targets. We employ techniques in functional genomics, biostatistics, data science, and next-generation sequencing to identify and characterize isoform-specific behaviors. By combining in vitro assays like transwell migration and spheroid formation with statistical modeling, we aim to uncover novel therapeutic targets and improve diagnostic precision. Students can gain hands-on experience in cell culture and bioinformatics, preparing them for advanced research in cancer biology and biomedical sciences.
Contact Information: Phone 620.235.4741 | Contact
My lab is investigating an antimicrobial protein from soybean as a potential antibiotic. Antibiotic resistance is a rapidly growing problem among human pathogens formerly easily controlled by existing drugs. We cloned a gene from soybean (Glycine max L.) encoding an enzyme possessing glucanase activity, potentially capable of degrading bacterial and fungal cell wall structures, resulting in abatement or termination of microbial growth. It has shown strong activity against several species of gram negative bacteria as well as against Charcoal Rot (Macrophomina phaseolina), a significant fungal pathogen of soybean, corn, cotton, and other crop plants. Analysis of purified recombinant protein from a yeast expression system is underway to determine toxicity of this antimicrobial agent.
Contact Information: phone 620.235.4746 | Contact
2023
Banerjee, T., Panchal, N., Sutton, C., Elliott, R., Patel, T., Kajal, K., Arogunyo, E., Koti, N., and Santra, S. "Tunable magneto-plasmonic nanosensor for sensitive detection of foodborne pathogens." Biosensors 13:109, 2023.
2022
Choi, J., Morey, K., Kumar, A., Neupane, D., Mishra, S. R., Perez, F., and Gupta, R. K. "Self-assembled cotton-like copper-molybdenum sulfide and phosphide as a bifunctional electrode for green energy storage and production." Materials Today Chemistry 24:100848, 2022.
Panchal, N., Jain, V., Elliott, R., Flint, Z., Worsley, P., Duran, C., Banerjee, T., and Santra, S. 2022. "Plasmon-enhanced bimodal nanosensors: An enzyme-free signal amplification strategy for ultrasensitive detection of pathogens." Analytical Chemistry 94:13968-13977, 2022.
2020
Shaw, Z., Patel, A., Butcher, T., Banerjee, T., Bean, R. and Santra, S. "Pseudo-branched polyester copolymer: an efficient drug delivery system to treat cancer." Biomaterials Science 8:1592-1603, 2020.
2016
Rider, V., Talbott, A., Bhusri, A., Krumsick, Z., Foster, S., Wormington, J. and Kimler, B. “Wingless (WNT) signaling is a progesterone target for rat uterine stromal cell proliferation.” Journal of Endocrinology 229:1-11, 2016.
2013
Ward, J. W., Rider, V., Abdou N. I., and Kimler, B. F. “Estradiol differentially regulates calreticulin: a potential link with abnormal T cell function in systemic lupus erythematosus?” Lupus 22:583-596, 2013.
2012
Weng, Ju-Lin, Samantha L. Young, David M. Gordon, David Claborn, Christine Petersen, Marcelo Ramalho-Ortigao. 2012.First Report of Phlebotomine Sand Flies (Diptera: Psychodidae) in Kansas and Missouri, and a PCR Method to Distinguish Lutzomyia shannoni From Lutzomyia vexator. J. Med. Entomol. 49:1163-1552.
2010
Abdou, N.I., and Rider, V. 2010. "Gender Differences in Autoimmune Diseases: Immune Mechanisms and Clinical Applications": in Principles of Gender Specific Medicine. M. Legato, ed., Elsevier, New York, pp 585-591.
2009
Rider, V., and Abdou, N. I. 2009. "Hormones-Epigenetic Contributors to Gender Biased Autoimmunity". in Epigenetics of Autoimmune Diseases. M. Zouali, ed., John Wiley & Sons Ltd. London, UK, 310-336.
Harries, P.A., Karuppaiah, P., Yu, W., Schoelz, J.E., Nelson, R.S. (2009) The Cauliflower mosaic virus protein P6 forms motile inclusions that traffic along actin microfilaments and stabilize microtubules. Plant Physiology 149(2):1005-1016.
Walters, E., Rider V., Abdou N.I., Greenwell C., Svojanovsky S., Smith P. and Kimler B.F. (2009) Estradiol targets T cell signaling pathways in human systemi lupus. Clinical Immunology 133:428-436.
2008
Gorjestani, S., Rider, V., Kimler, B.F., Greenwell, C., and Abdou, N.I. "Extracellular Signal Regulated Kinase1/2 Signaling in SLE T Cells is Influenced by Estrogen and Disease Activity." Lupus, 17: 548-554, 2008.
Abdou, N. I., Rider, V., Greenwell, C., Li, X. and Kimler B.F. "Fulvestrant (Faslodex) an Estrogen Selective Receptor Downregulator, in Therapy of Females with Systemic Lupus Erythematosus: Clinical, Serologic, Bone Density, and T Cell Activation Marker Studies: A Double-Blind Placebo-Controlled Trial." Journal of Rheumatology, 35: 797- 803, 2008.
Harries, P.A., Karuppaiah, P., Bhat, S., Nelson, R.S. (2008) Tobacco mosaic virus 126-kDa protein increases the susceptibility of Nicotiana tabacum to other viruses and its dosage affects virus-induced gene silencing. Mol. Plant-Microbe Interact. 21:1539-1548.
Harries, P.A., Nelson, R.S. (2008) Movement of Viruses in Plants. Encyclopedia of Virology, 3rd Edition. pp. 348-355. Elsevier Press.
2007
Rider, V., Li, X., and Abdou, N.I. "Hormonal Influences in the Expression of Systemic Lupus Erythematosus." in Systemic Lupus Erythematosus: A Companion to Rheumatology. G. C. Tsokos, P.C. Gordon, J. S. Smolen, eds., Elsevier, New York, NY, 87-94, 2007.
2006
Rider, V., Li, X., Peterson, G., Dawson J., Kimler B.F., and Abdou, N.I. "Differential Expression of Estrogen Receptors in Females with Systemic Lupus Erythematosus". Journal of Rheumatology 33: 1093-1101, 2006.
Li, X., Rider, V., Kimler, B.F., and Abdou, N.I. "Estrogen Does Not Regulate CD154 mRNA Stability in SLE T Cells." Lupus 15: 1-6, 2006.
Rider, V., Isuzugawa, K., Twarog, M., Jones, S., Cameron, B., Imakawa, K., and Fang, J. "Progesterone Initiates Wnt-β-catenin Signaling But Estradiol is Required for Nuclear Activation and Synchronous Proliferation of Rat Uterine Stromal Cells." Journal of Endocrinology 191:1-13, 2006.
Cove, D.J., Bezanilla, M.B., Harries, P.A., Quatrano, R.S. (2006) Mosses as model systems for the study of metabolism and development. Annual Review of Plant Biology, 57, 497-520.
Student Scholar | Mentor |
Megan Abdilla | Dr. Gashti |
Sara Akhtar | Dr. Ward |
Gavin Doubrava | Dr. McAfee |
Hannah Eckstein | Dr. Harries |
Noah Freiburger | Dr. Gashti |
Brett Gibson | Dr. Harries |
Auditya Jain | Dr. Harries |
Morgan Leeper | Dr. Pretot |
Rylan Mason | Dr. Snow |
Loryn Moser | Dr. Covert-Miller |
Caitlynn Tate | Dr. Martins |
Clarissa Wedman | Dr. Brodsky |
Student Scholar | Mentor |
Alexandra Robinson | Dr. Gupta |
Anjali Gupta | Dr. Gupta |
Sebastian Henry | Dr. Ward |
Zachary Todd | Dr. McAfee |
Kelsie Tucker | Dr. Chung |
Student Scholar | Mentor |
Ayushee Dasgupta | Dr. Ghosh |
2024
2023
2022
2021
2020
2019
2018
2017
2016
2015
2014
2013
2012
2011
2010
2009
2008
2007
2006
2005
2004